| Class | Departure Station | Arrival Station | Departure | Arrival | Travel time |
|---|---|---|---|---|---|
| Semi Sleeper | Retiro Bus Station | Asuncion Bus Station | 12:00 | 05:30 | 17h 30m |
| Semi Sleeper | Retiro Bus Station | Asuncion Bus Station | 13:30 | 07:00 | 17h 30m |
| Semi Sleeper | Retiro Bus Station | Asuncion Bus Station | 18:00 | 12:00 | 18h 0m |
| Semi Sleeper | Retiro Bus Station | Asuncion Bus Station | 18:30 | 12:15 | 17h 45m |
| Semi Sleeper | Retiro Bus Station | Asuncion Bus Station | 20:00 | 13:30 | 17h 30m |
| 1st Class Sleeper | Retiro Bus Station | Asuncion Bus Station | 12:00 | 05:30 | 17h 30m |
| 1st Class Sleeper | Retiro Bus Station | Asuncion Bus Station | 13:30 | 07:00 | 17h 30m |
| 1st Class Sleeper | Retiro Bus Station | Asuncion Bus Station | 18:00 | 12:00 | 18h 0m |
| 1st Class Sleeper | Retiro Bus Station | Asuncion Bus Station | 18:30 | 12:15 | 17h 45m |
| 1st Class Sleeper | Retiro Bus Station | Asuncion Bus Station | 20:00 | 13:30 | 17h 30m |
| Semi Sleeper | Asuncion Bus Station | Retiro Bus Station | 13:30 | 07:30 | 18h 0m |
| Semi Sleeper | Asuncion Bus Station | Retiro Bus Station | 16:00 | 10:30 | 18h 30m |
| Semi Sleeper | Asuncion Bus Station | Retiro Bus Station | 16:30 | 11:30 | 19h 0m |
| Semi Sleeper | Asuncion Bus Station | Retiro Bus Station | 16:35 | 10:30 | 17h 55m |
| 1st Class Sleeper | Asuncion Bus Station | Retiro Bus Station | 13:30 | 07:30 | 18h 0m |
| 1st Class Sleeper | Asuncion Bus Station | Retiro Bus Station | 16:00 | 10:30 | 18h 30m |
| 1st Class Sleeper | Asuncion Bus Station | Retiro Bus Station | 16:30 | 11:30 | 19h 0m |
| 1st Class Sleeper | Asuncion Bus Station | Retiro Bus Station | 16:35 | 10:30 | 17h 55m |
| Semi Sleeper | Asuncion Bus Station | Terminal de Corrientes | 00:00 | 06:00 | 6h 0m |
| 1st Class Sleeper | Asuncion Bus Station | Terminal de Corrientes | 00:00 | 06:00 | 6h 0m |